Sexually Transmitted Infection Considerations for Transgender and Gender Expansive Persons

Transgender and gender expansive persons (TGE) are at increased risk for sexually transmitted infections (STIs) compared with other demographic groups and face barriers to health care access that may limit their ability to obtain testing and treatment. Herein, we highlight unique, yet vital, aspects of STI screening and treatment in TGE persons utilizing a gender-affirming care approach, including best practices for gender-inclusive care and special considerations for TGE persons who have undergone gender-affirming hormone therapy and/or surgery. Opportunities exist to improve sexual health in TGE persons, which can be achieved through culturally competent, gender inclusive STI testing and treatment.