Optimization of the manufacturing process of a pediatric omeprazole enteric pellets suspension: Full Factorial Design
The findings suggest that the optimal vehicle for the administration of omeprazole enteric pellets in suspension is the formulation comprising Labrafil M 1944 CS, Span 80, and Aerosil<sup>®</sup> 200. This study has paved the way for an oily suspension vehicle, opening new avenues of research for developing pediatric omeprazole formulations that fulfill gastro-resistance requirements.
Authors
- Josep M. Suñé‐Negre (ORCID: https://orcid.org/0000-0003-1368-2699)
- Marc Suñé-Pou (ORCID: https://orcid.org/0000-0002-0730-3077)
- Pilar Pérez‐Lozano (ORCID: https://orcid.org/0000-0001-6899-066X)
- Blanca Chiclana-Rodríguez (ORCID: https://orcid.org/0000-0002-9279-536X)
- Khadija Rouaz-El-Hajoui (ORCID: https://orcid.org/0000-0002-7819-2773)
- Àlex Fraschi-Nieto (ORCID: https://orcid.org/0000-0002-2070-3489)
- E. García-Montoya
- Xavier Mula-Roldán
Institutions
- Institut d'Investigació Biomédica de Bellvitge (ES)
- PharmacoGenetics (China) (CN)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Drug Development and Industrial Pharmacy
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1080/03639045.2025.2476651
- Primary Topic
- Pharmaceutical studies and practices
- Type
- article
- Field-Weighted Citation Impact
- 0.00