Phosphatidylserine induce thrombotic tendency and liver damage in obstructive jaundice
These results highlight the pathogenic activity of PS + cells and MPs in promoting a prothrombotic environment and liver damage in OJ. As such, lactadherin, a PS blockade, may be a viable therapeutic strategy for treating such patients.
Authors
- Chuwei Zheng
- Lu Gao (ORCID: https://orcid.org/0000-0003-1632-5101)
- Jinming Zhang (ORCID: https://orcid.org/0000-0001-7400-4643)
- Xiaoguang Wang (ORCID: https://orcid.org/0000-0003-0118-4772)
- Muxin Yu
- Rong Peng (ORCID: https://orcid.org/0000-0003-4478-4225)
Institutions
- Jiaxing University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1186/s12876-025-03739-9
- Citations
- 2
- Primary Topic
- Neonatal Health and Biochemistry
- Type
- article
- Field-Weighted Citation Impact
- 6.99
Funders
- National Natural Science Foundation of China
- Medical Science and Technology Project of Zhejiang Province
- Natural Science Foundation of Zhejiang Province