Interactions between gilthead seabream intestinal transcriptome and microbiota upon Enteromyxum leei infection: a multi–omic approach
Intestinal microbiota and local host gene expression showed significant changes upon en enteromyxosis. The detected activation of the host immune response was not exclusively linked to the parasite infection but also to changes in microbiota, demonstrating the key role of the different components of the mucosal system during disease. These results provided different datasets of bacterial taxa and microbial and host transcripts that will allow a better understanding of host-microbiota-parasite interactions and can serve as starting points for studying and evaluating mucosal health in aquaculture during parasitosis or other diseases.
Authors
- Jaume Pérez‐Sánchez (ORCID: https://orcid.org/0000-0003-2506-1523)
- Socorro Toxqui-Rodríguez (ORCID: https://orcid.org/0000-0001-9657-3361)
- Detmer Sipkema (ORCID: https://orcid.org/0000-0003-3836-219X)
- Itziar Estensoro (ORCID: https://orcid.org/0000-0002-6218-2191)
- M. Carla Piazzon (ORCID: https://orcid.org/0000-0002-4949-8984)
- Raquel Del Pozo
- Ariadna Sitjà‐Bobadilla (ORCID: https://orcid.org/0000-0002-7473-3413)
- Ricardo Domingo-Bretón (ORCID: https://orcid.org/0000-0003-2933-236X)
Institutions
- Instituto de Acuicultura Torre de la Sal (ES)
- Wageningen University & Research (NL)
Publication Details
- Journal
- Animal Microbiome
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1186/s42523-025-00388-x
- Citations
- 5
- Primary Topic
- Myxozoan Parasites in Aquatic Species
- Type
- article
- Field-Weighted Citation Impact
- 4.68
Funders
- Generalitat Valenciana
- Ministerio de Ciencia e Innovación
- Agencia Estatal de Investigación
- H2020 Marie Skłodowska-Curie Actions