VITAMIN D IMPACT ON STRESS AND COGNITIVE DECLINE IN OLDER ROMANIAN ADULTS

Vitamin D plays a key role in ageing-related cellular processes, such as inflammation, oxidative stress and mitochondrial dysfunction.Vitamin D deficiency is prevalent among older adults and has been linked to cognitive decline, mood disorders and various age-related diseases.This study evaluated the correlation between serum vitamin D levels and stress resilience, cognitive decline and successful ageing in older Romanian adults.A cross-sectional clinical trial was conducted with 89 participants over 55.Serum vitamin D levels were measured using chemiluminescence analysis.At the same time, the cognitive function was assessed through the Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MOCA) and the Geriatric Depression Scale.Stress and resilience were evaluated using the Perceived Stress Scale and Siebert Resilience Test.Low vitamin D levels have been associated with cognitive impairment, as measured by the MMSE and MOCA.However, no significant relationship was found between vitamin D levels and stress or resilience scores.This study indicates that vitamin D may play a significant role in preventing cognitive decline among older adults; however, its effects on stress and resilience necessitate further investigation. RezumatVitamina D joac un rol important n procesele celulare asociate cu mbtrnirea, cum ar fi inflamaia, stresul oxidativ i disfuncia mitocondrial.Carena de vitamin D este rspndit n rndul adulilor n vrst i a fost legat de deficitul cognitiv, tulburrile de dispoziie i alte boli ale vrstnicului.Acest studiu i-a propus s evalueze corelaia dintre nivelurile serice de vitamin D i rezistena la stres, declinul cognitiv i mbtrnirea cu succes la vrstnicii din Romnia.Un studiu clinic transversal a fost efectuat cu 89 de participani avnd vrsta peste 55 de ani.Nivelurile serice de vitamin D au fost msurate folosind analiza de chemiluminiscen, n timp ce funcia cognitiv a fost evaluat prin Mini-Mental State Examination (MMSE), Montreal Cognitive Assessment (MOCA) i Geriatric Depression Scale.Stresul i reziliena au fost evaluate utiliznd Scala de stres perceput i Testul de rezilien psihic Siebert.A fost identificat o corelaie semnificativ ntre nivelurile sczute de vitamina D i afectarea cognitiv, msurat de MMSE i MOCA.Cu toate acestea, nu a fost gsit nicio relaie semnificativ ntre nivelurile de vitamina D i scorurile de stres sau rezisten.Acest studiu sugereaz c vitamina D joac un rol n prevenirea declinului cognitiv la vrstnici, dar impactul su asupra stresului i rezilienei psihice necesit investigaii suplimentare.