Comparative Structure Activity Relationship Characterization of the Biosimilar BAT1806/BIIB800 to Reference Tocilizumab
Comparative structure activity relationship characterization of BAT1806/BIIB800 and TCZ indicated that there are no relevant differences in quality attributes between BAT1806/BIIB800 and reference TCZ. Observed differences between BAT1806/BIIB800 and TCZ had no functional impact on BAT1806/BIIB800. The results support the conclusion that BAT1806/BIIB800 is similar to TCZ.
Authors
- Hans C. Ebbers (ORCID: https://orcid.org/0000-0002-9553-9863)
- Zhuxiang Li
- Shengfeng Li
- Cuihua Liu (ORCID: https://orcid.org/0000-0003-1551-1818)
- Suli Liu (ORCID: https://orcid.org/0000-0002-7126-4631)
- Yujie Liu (ORCID: https://orcid.org/0000-0001-5949-9545)
- Jianhua Xie (ORCID: https://orcid.org/0000-0002-3906-1260)
- Di Cao (ORCID: https://orcid.org/0000-0002-1205-1556)
- L. Engle
- Xiong Mei
Institutions
- Biogen (United States) (US)
- Yahoo (United Kingdom) (GB)
- Ta Solutions (China) (CN)
- Biogen (Switzerland) (CH)
Publication Details
- Journal
- BioDrugs
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1007/s40259-024-00698-7
- Citations
- 2
- Primary Topic
- Biosimilars and Bioanalytical Methods
- Type
- article
- Field-Weighted Citation Impact
- 1.59
Funders
- Biogen