Molecular characterization of colorectal cancer (CRC) using next generation sequencing (NGS) in bridging the gap between research and clinical practice: from biomarker discovery to clinical implementation
This is the first NGS-based molecular study on FFPE-CRC tissues in hospital-USM that showed the most upregulated variants in CRC and identified nine genes as crucial pathogenic variants.
Authors
- Wan Mohd Nazri Wan Zainon
- Hafeez Abiola Afolabi (ORCID: https://orcid.org/0000-0002-1120-4100)
- Md Salzihan Md Salleh (ORCID: https://orcid.org/0000-0001-6691-4962)
- Sameer Badri Al-Mhanna (ORCID: https://orcid.org/0000-0001-9063-0185)
- Ewe Seng Ch’ng (ORCID: https://orcid.org/0000-0001-8831-8678)
- Siti Norasikin Mohd Nafi (ORCID: https://orcid.org/0000-0002-0642-0909)
- Rashidat Folashade Elesho
- Y. Wada (ORCID: https://orcid.org/0000-0003-0003-9581)
- Ahmad Aizat Abdul Aziz (ORCID: https://orcid.org/0000-0002-9822-2001)
- Zaidi Zakaria
- Ahmad Adebayo Irekola
Institutions
- Ahmadu Bello University (NG)
- Howard University (US)
- Universiti Sains Malaysia (MY)
- Hospital Universiti Sains Malaysia (MY)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1007/s12672-025-01960-2
- Citations
- 3
- Primary Topic
- Colorectal Cancer Treatments and Studies
- Type
- article
- Field-Weighted Citation Impact
- 3.14