A Peptide Derived from Nectin-4 Increases Cisplatin Cytotoxicity in Cell Lines and Cells from Ovarian Cancer Patients’ Ascites
These results suggest that targeting the cell-cell adhesive property of cancer cells could serve as a new approach to augment the cytotoxic effect of chemotherapy and potentially reduce disease recurrence in ovarian cancer patients.
Authors
- Alexandra Schefter
- Amy P.N. Skubitz (ORCID: https://orcid.org/0000-0003-4672-3450)
- Christoph Walz
- Kristin L.M. Boylan (ORCID: https://orcid.org/0000-0001-9003-8763)
Institutions
- University of Minnesota (US)
- University of Minnesota Medical Center (US)
Publication Details
- Journal
- Cancers
- Published
- 2025-03-06
- DOI
- https://doi.org/10.3390/cancers17050901
- Citations
- 3
- Primary Topic
- Ovarian cancer diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.09
Funders
- Minnesota Ovarian Cancer Alliance
- Randy Shaver Cancer Research and Community Fund