The Impact of Tartrazine on DNA Methylation, Histone Deacetylation, and Genomic Stability in Human Cell Lines
These results suggest that TRZ may play a role in carcinogenesis and epigenetic modifications. The observed upregulation of <i>DNMTs</i> and <i>HDACs</i>, coupled with increased DNA damage, highlights the potential risks associated with TRZ exposure. Further research is necessary to explore these mechanisms and assess their implications for human health.
Authors
- Tímea Varjas (ORCID: https://orcid.org/0000-0002-4950-0669)
- Bence László Raposa (ORCID: https://orcid.org/0000-0001-9551-8440)
- Afshin Zand (ORCID: https://orcid.org/0000-0001-5656-089X)
- Ádám Molnár (ORCID: https://orcid.org/0000-0002-7581-9796)
- John M. Macharia (ORCID: https://orcid.org/0000-0002-7535-9478)
- István Szabó (ORCID: https://orcid.org/0000-0001-7450-4728)
- Gellért Gerencsér
Institutions
- University of Pecs (HU)
Publication Details
- Journal
- Nutrients
- Published
- 2025-03-06
- DOI
- https://doi.org/10.3390/nu17050913
- Citations
- 5
- Primary Topic
- Dye analysis and toxicity
- Type
- article
- Field-Weighted Citation Impact
- 3.76