<italic>In vitro</italic> cultured calculus bovis alleviates cerebral ischemia/reperfusion injury through regulating microglial polarization and inhibiting NLRP3
ICCB exerts a protective effect against CIRI by mitigating neuroinflammation, through the reduction of M1 microglial polarization, promotion of M2 conversion, and suppression of the NLRP3/ASC/caspase-1 signaling pathway.
Authors
- T. Chu
- Fengmei Qiu (ORCID: https://orcid.org/0000-0003-2189-7649)
- Jingwen Chen (ORCID: https://orcid.org/0000-0002-5756-3336)
- Lingfeng Wang (ORCID: https://orcid.org/0000-0003-1658-9860)
- Wei Zhang (ORCID: https://orcid.org/0000-0003-1768-0885)
- Zhongya Pan
- Zhen Huang (ORCID: https://orcid.org/0000-0003-1433-1428)
- Xiaoming Zhong
Institutions
- Zhejiang Chinese Medical University (CN)
- Jinhua Academy of Agricultural Sciences (CN)
Publication Details
- Journal
- Journal of Zhejiang University (Medical Sciences)
- Published
- 2025-03-06
- DOI
- https://doi.org/10.3724/zdxbyxb-2024-0573
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00