Assessing Oral Health Related Quality of Life After Third Molar Extraction with Ozonized Water: A Randomized Triple Blind Spit-mouth Clinical Trial

Purpose: The present study evaluated the oral health related quality of life of patients that were submitted to removal of lower third molars with alveolar irrigation using double distilled ozonized water or only double distilled water during the surgical procedure. Methods: In this split mouth study, 21 patients were randomized into group 1 (T1 – side of the mouth that received ozonized double-distilled water during surgical procedure) and group 2 (T2 – group that received double-distilled water only during surgical procedure). Each patient was submitted to 2 surgical procedures, at least 4 weeks apart from each other. A questionnaire on OHRQoL was completed by each patient after the surgical procedure and 7 days after, as well as another questionnaire after suture removal. Results: It was included 8 men and 12 women. For social isolation dimension, the ozonized water showed better results than control group (p = 0.043). Eighty percent of patients in test group reported pain and edema as a cause of social isolation after surgery (p = 0.013). Ability to feed and variations in diet dimension shows that 5% (n = 1) of patients in T1 did not notice any change in these skills, while none of the patients at T2 recovered from surgery without any change in their eating ability and diet. Conclusion: Ozone therapy can positively affect patients' OHRQoL in terms of pain and swelling and satisfaction with treatment.