Antifungal and wound healing potential of calendula officinalis for dental use

Aim: To demonstrate the antifungal and healing properties of Calendula officinalis. Methods: We included four assays: inhibition halo, germicidal test, cytotoxicity test, and scratch test. Results: The extract at 100% and 50% concentrations was effective, and both presentations (Calendula officinalis extract and Calendula officinalis infusion) exhibited no cytotoxic effects. Furthermore, the infusion demonstrated a high healing effect without affecting the morphology of the cell monolayer and promoted fibroblastic proliferation. The extract did not show the expected healing results. Conclusions: Calendula officinalis holds considerable potential for further research across various biological processes, highlighting its promise as a subject for continued investigation.