Digital Twins, Extended Reality, and Artificial Intelligence in Manufacturing Reconfiguration: A Systematic Literature Review

This review draws on a systematic literature review and bibliometric analysis to examine how Digital Twins (DTs), Extended Reality (XR), and Artificial Intelligence (AI) support the reconfiguration of Cyber–Physical Systems (CPSs) in modern manufacturing. The review aims to provide an updated overview of these technologies’ roles in CPS reconfiguration, summarize best practices, and suggest future research directions. In a two-phase process, we first analyzed related work to assess the current state of assisted manufacturing reconfiguration and identify gaps in existing reviews. Based on these insights, an adapted PRISMA methodology was applied to screen 165 articles from the Scopus and Web of Science databases, focusing on those published between 2019 and 2025 addressing DT, XR, and AI integration in Reconfigurable Manufacturing Systems (RMSs). After applying the exclusion criteria, 38 articles were selected for final analysis. The findings highlight the individual and combined impact of DTs, XR, and AI on reconfiguration processes. DTs notably reduce reconfiguration time and improve system availability, AI enhances decision-making, and XR improves human–machine interactions. Despite these advancements, a research gap exists regarding the combined application of these technologies, indicating potential areas for future exploration. The reviewed studies recognized limitations, especially due to diverse study designs and methodologies that may introduce risks of bias, yet the review offers insight into the current DT, XR, and AI landscape in RMS and suggests areas for future research.