One-stage revision for postoperative infection following internal fixation of hip fractures: a report of three cases

Postoperative infection following internal fixation of hip fractures is a rare but severe complication that can significantly impact patient outcomes. Conventional treatment typically involves a two-stage revision approach. This study investigates the efficacy of a one-stage revision procedure for managing infections after internal fixation of hip fractures, based on three clinical cases (one femoral neck fracture and two intertrochanteric fractures) treated at our institution. The patients underwent one-stage revision surgery, which included comprehensive debridement and a 2-week course of vancomycin administered both intravenously and via joint cavity injection. Discharge was permitted when inflammatory markers had normalized, bacterial cultures returned negative, and the patients' conditions were stabilized. Post-discharge, patients continued a 6-week course of oral rifampicin and ciprofloxacin. At the 1-year follow-up, none of the patients experienced pain or restricted range of motion, and all achieved Harris hip scores greater than 85. These results suggest that for infections following internal fixation of hip fractures, a one-stage revision, combined with thorough debridement and an adequate course of antibiotics (assuming a clear pathogen is identified), can effectively obviate the need for secondary surgeries, reduce healthcare costs, and minimize patient complications. This approach provides valuable insights and alternative strategies for managing postoperative hip fracture infections in clinical settings.

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Publication Details

Journal
Discover Medicine
Published
2025-03-06
DOI
https://doi.org/10.1007/s44337-025-00261-5
Primary Topic
Orthopedic Infections and Treatments
Type
article
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article

One-stage revision for postoperative infection following internal fixation of hip fractures: a report of three cases

Xuewen Kang, Yafei Cao, Shenghu Zhou, Peijie Li et al.
Discover Medicine
Orthopedic Infections and Treatments
article

One-stage revision for postoperative infection following internal fixation of hip fractures: a report of three cases

Xuewen Kang, Yafei Cao, Shenghu Zhou, Peijie Li, Jiahuan Li, Fei Tan, Jiankang Zeng, Yongjie Qiao
article en

Abstract

Postoperative infection following internal fixation of hip fractures is a rare but severe complication that can significantly impact patient outcomes. Conventional treatment typically involves a two-stage revision approach. This study investigates the efficacy of a one-stage revision procedure for managing infections after internal fixation of hip fractures, based on three clinical cases (one femoral neck fracture and two intertrochanteric fractures) treated at our institution. The patients underwent one-stage revision surgery, which included comprehensive debridement and a 2-week course of vancomycin administered both intravenously and via joint cavity injection. Discharge was permitted when inflammatory markers had normalized, bacterial cultures returned negative, and the patients' conditions were stabilized. Post-discharge, patients continued a 6-week course of oral rifampicin and ciprofloxacin. At the 1-year follow-up, none of the patients experienced pain or restricted range of motion, and all achieved Harris hip scores greater than 85. These results suggest that for infections following internal fixation of hip fractures, a one-stage revision, combined with thorough debridement and an adequate course of antibiotics (assuming a clear pathogen is identified), can effectively obviate the need for secondary surgeries, reduce healthcare costs, and minimize patient complications. This approach provides valuable insights and alternative strategies for managing postoperative hip fracture infections in clinical settings.

Discover MedicineVol. 2(1)
Gansu University of Traditional Chinese Medicine (CN), People's Liberation Army 401 Hospital (CN), Lanzhou University Second Hospital (CN), Lanzhou University (CN)
Good health and well-being
Openalex Percentile: Top 93%
Orthopedic Infections and Treatments
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