Quantum super-resolution microscopy by photon statistics and structured light
Reaching high-resolution imaging of delicate samples at a low-intensity level is a major challenge in microscopy. Here, we present and experimentally implement an advanced quantum super-resolution imaging technique based on photon statistics measurement. Our reconstruction algorithm adapts to any kind of non-Poissonian emitters, outperforming the corresponding classical SOFI method, in particular in low-light conditions. It offers sub-diffraction resolution improvement that scales with the j , where j is the highest-order central moments of the photocounts. More remarkably, we show that in combination with structured illumination, an improvement of j + j can be reached, providing a promising avenue for non-invasive super-resolution microscopy.
Authors
- Marco Genovese (ORCID: https://orcid.org/0000-0001-9186-8849)
- Fabio Picariello (ORCID: https://orcid.org/0000-0003-3773-9768)
- Pauline Boucher (ORCID: https://orcid.org/0000-0002-3046-3503)
- Ivo Pietro Degiovanni (ORCID: https://orcid.org/0000-0003-0332-3115)
- S. Ditalia Tchernij (ORCID: https://orcid.org/0000-0002-2639-5229)
- Ivano Ruo Berchera (ORCID: https://orcid.org/0000-0003-3131-8866)
- Elena Losero (ORCID: https://orcid.org/0000-0001-9531-9695)
Institutions
- Quanta Technology (United States) (US)
- Istituto Nazionale di Fisica Nucleare (IT)
- University of Turin (IT)
Publication Details
- Journal
- Optica
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1364/optica.540264
- Citations
- 8
- Primary Topic
- Advanced Fluorescence Microscopy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 13.07