Endoscopic Ultrasound-Guided Anastomoses of the Gastrointestinal Tract: A Multicentric Experience
This multicenter retrospective study included patients undergoing EUS-guided GI anastomoses from 2016 to 2023. Indications for EUS-guided anastomosis were GOO, ALS or patients with altered anatomy needing endoscopic interventions. The primary outcome was technical success, while secondary outcomes included clinical success, safety, lumen-apposing metal stent (LAMS) patency, and the need for reinterventions. A total of 216 patients (mean age 64.5 [±13.94] years; 49.1% males) were included. In total, 149 cases (69%) were GOO, 44 (20.4%) cases were bilioenteric anastomotic strictures or lithiasis in altered anatomy, 14 cases (6.5%) were ALS, and 9 patients (4.2%) were for ERCP in altered anatomy after EUS-GG. Overall, EUS-GE was performed in 181 patients (83.8%), EUS-JJ in 44 cases (20.4%), and EUS-GG in 10 (4.6%). Technical success was 94.91%, and clinical success was 93.66%. The adverse event (AE) rate was 11.1%. The reintervention rate was 7.69%. The median follow-up was 85 days. In conclusions, EUS-guided GI anastomoses are technically feasible and safe in both malignant and benign diseases.
Authors
- Edoardo Forti (ORCID: https://orcid.org/0000-0002-7400-2979)
- Stefano Francesco Crinò (ORCID: https://orcid.org/0000-0003-4560-8741)
- Alessandro Fugazza (ORCID: https://orcid.org/0000-0003-0485-4903)
- Cecilia Binda (ORCID: https://orcid.org/0000-0003-1148-9684)
- Alessandro Repici (ORCID: https://orcid.org/0000-0002-1621-6450)
- Marcello Fabio Maida (ORCID: https://orcid.org/0000-0002-4992-9289)
- Giovanni Aragona
- Andrea A. Anderloni (ORCID: https://orcid.org/0000-0002-1021-0031)
- Giacomo Emanuele Maria Rizzo (ORCID: https://orcid.org/0000-0001-9335-6740)
- Carlo Fabbri (ORCID: https://orcid.org/0000-0003-0670-9910)
- Chiara Coluccio (ORCID: https://orcid.org/0000-0002-8791-7764)
- Giuseppe Vanella (ORCID: https://orcid.org/0000-0001-7280-1761)
- Ilaria Tarantino (ORCID: https://orcid.org/0000-0001-8791-3395)
- Aurelio Mauro (ORCID: https://orcid.org/0000-0002-8475-5464)
- Andrea Lisotti (ORCID: https://orcid.org/0000-0002-7724-7402)
- Francesco Maria Di Matteo
Institutions
- Humanitas University (IT)
- Vita-Salute San Raffaele University (IT)
- Università Campus Bio-Medico (IT)
- Università degli Studi di Enna Kore (IT)
- University of Pavia (IT)
- Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda (IT)
- Azienda Unità Sanitaria Locale Piacenza (IT)
- Azienda Unità Sanitaria Locale Della Romagna (IT)
- Campus Bio Medico University Hospital (IT)
- Policlinico San Matteo Fondazione (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- IRCCS Humanitas Research Hospital (IT)
- Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT)
- Istituto Mediterraneo per i Trapianti e Terapie ad Alta Specializzazione (IT)
- University of Palermo (IT)
- University of Bologna (IT)
Publication Details
- Journal
- Cancers
- Published
- 2025-03-06
- DOI
- https://doi.org/10.3390/cancers17050910
- Citations
- 6
- Primary Topic
- Esophageal and GI Pathology
- Type
- article
- Field-Weighted Citation Impact
- 12.04