Clinical and immunological relationships in patients with early schizophrenia
Changes in the concentrations of pro-inflammatory and anti-inflammatory interleukins, which are involved in the development of a nonspecific immune response as part of the systemic inflammatory response in patients with early schizophrenia during remission, have been demonstrated. The results suggest that in patients with the first episode of schizophrenia, the activation of immune inflammation plays a significant role in the development of the disease. Over time, such activation may stabilize and is associated with a greater severity of psychopathological symptoms.
Authors
- V. V. Dorofeykov (ORCID: https://orcid.org/0000-0002-7272-1654)
- V.S. Serazetdinova (ORCID: https://orcid.org/0000-0002-3404-0786)
- Margarita Mayorova (ORCID: https://orcid.org/0000-0002-4932-4749)
- Н. Н. Петрова (ORCID: https://orcid.org/0000-0003-4096-6208)
Institutions
- St Petersburg University (RU)
- Federal State Budget Educational Institution of Higher Education «Lesgaft National State University of Physical Education, Sport and Health, St. Petersburg» (RU)
- Institute of the Human Brain (RU)
Publication Details
- Journal
- S S Korsakov Journal of Neurology and Psychiatry
- Published
- 2025-03-06
- DOI
- https://doi.org/10.17116/jnevro202512502135
- Citations
- 1
- Primary Topic
- Tryptophan and brain disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.58