Dual Targeting of Neuropilin-1 and Glucose Transporter for Efficient Fluorescence Imaging of Cancer
This study highlighted the efficient targeting and sustained retention of the dual-target heterodimeric fluorescent probe NGF, binding to NRP1 and GLUT1 receptors. These findings suggest significant potential for clinical applications in early cancer detection and fluorescence image-guided surgery.
Authors
- Jian Yang (ORCID: https://orcid.org/0000-0001-7876-9475)
- Zhenhua Wang (ORCID: https://orcid.org/0000-0001-5501-1768)
- Jianwei Zhu (ORCID: https://orcid.org/0000-0002-0810-2189)
- Zhou Can
Institutions
- Shanghai University (CN)
- Jiading District Central Hospital (CN)
- Shanghai University of Medicine and Health Sciences (CN)
Publication Details
- Journal
- Molecular Imaging and Biology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1007/s11307-025-01993-7
- Citations
- 1
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94