TFE3 fusion proteins promote the progression of TFE3 rearranged renal cell carcinoma via enhancing chaperone-mediated lipophagy
TFE3 fusion proteins facilitated the progression of TFE3 rRCC through enhancing the degradation of LDs via chaperone-mediated lipophagy. LAMP2A could serve as a novel potential prognostic biomarker and therapeutic targets.
Authors
- Yanwen Lu
- Xiang Da Dong (ORCID: https://orcid.org/0000-0001-9324-1281)
- Lei Yang (ORCID: https://orcid.org/0000-0001-6328-6518)
- Guijuan Chen
- Dongmei Li (ORCID: https://orcid.org/0000-0003-3819-355X)
- Yi Chen (ORCID: https://orcid.org/0000-0002-4404-3948)
- Wenliang Ma
- Weidong Gan
Institutions
- Nanjing Drum Tower Hospital (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Cell Communication and Signaling
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1186/s12964-025-02117-y
- Citations
- 2
- Primary Topic
- Endoplasmic Reticulum Stress and Disease
- Type
- article
- Field-Weighted Citation Impact
- 2.30