Goserelin 3-month depot shows non-inferiority to the monthly formulation in U.S. patients with premenopausal breast cancer: a real-world evidence study

This real-world analysis indicates that 3-month goserelin 10.8 mg is non-inferior to monthly 3.6 mg among premenopausal women with breast cancer in terms of 12-month rwEFS rate. These findings may support the use of the 3-month goserelin 10.8 mg as an alternative treatment option to monthly goserelin 3.6 mg for this patient population.

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Publication Details

Journal
Breast Cancer Research and Treatment
Published
2025-03-06
DOI
https://doi.org/10.1007/s10549-025-07656-z
Primary Topic
Breast Cancer Treatment Studies
Type
article
Field-Weighted Citation Impact
0.00
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article

Goserelin 3-month depot shows non-inferiority to the monthly formulation in U.S. patients with premenopausal breast cancer: a real-world evidence study

Jon G. Tepsick, Lonnie Brent, Y. Wang, Virginia Kaklamani et al.
Breast Cancer Research and Treatment
Breast Cancer Treatment Studies
article

Goserelin 3-month depot shows non-inferiority to the monthly formulation in U.S. patients with premenopausal breast cancer: a real-world evidence study

Jon G. Tepsick, Lonnie Brent, Y. Wang, Virginia Kaklamani, Kelly McCann, Noran Osman, Nancy Martin, Joan Cannon, Vincent A. Miller, Prithviraj Vikramsinh Mandora
article en

Abstract

This real-world analysis indicates that 3-month goserelin 10.8 mg is non-inferior to monthly 3.6 mg among premenopausal women with breast cancer in terms of 12-month rwEFS rate. These findings may support the use of the 3-month goserelin 10.8 mg as an alternative treatment option to monthly goserelin 3.6 mg for this patient population.

Breast Cancer Research and TreatmentVol. 211(2)
University of California, Los Angeles (US), The University of Texas at San Antonio Health Science Center (US), Deerfield (United States) (US), Concert Pharmaceuticals (United States) (US)
Openalex Percentile: Top 95%
Breast Cancer Treatment Studies
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Goserelin 3-month depot shows non-inferiority to the monthly formulation in U.S. patients with premenopausal breast cancer: a real-world evidence study — Jon G. Tepsick, Lonnie Brent, et al. · Breast Cancer Research and Treatment (2025) | TGRS Research Map | TGRS