Porcine Sub-Retinal Pigment Epithelium Deposits: A Model for Dry Age-Related Macular Degeneration With Comparison to Human Drusen
Due to their compositional similarity to human drusen, ex vivo "drusen-in-a-dish" systems represent a potentially robust and cost-effective model for both studying the pathobiology of drusen biogenesis and screening novel therapeutics aimed at limiting drusen formation.
Authors
- Christine A. Curcio (ORCID: https://orcid.org/0000-0001-9769-1538)
- Daniel M. Lipinski (ORCID: https://orcid.org/0000-0001-7828-614X)
- Erika Shaw
- David M. Anderson (ORCID: https://orcid.org/0000-0002-1049-3158)
- Kevin L. Schey
- Ramesh Periasamy
Institutions
- Vanderbilt University (US)
- Medical College of Wisconsin (US)
- University of Alabama at Birmingham (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1167/iovs.66.3.18
- Citations
- 1
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.71