Treatment of non-small cell lung cancer: advances following the introduction of PET-CT and IMRT/VMAT

In summary, refined RT/RCT strategies with PET-CT and IMRT/VMAT enable the intensification of multimodal treatment. Reduction of toxicities with IMRT/VMAT widens the therapeutic window. The coincidence of intensified treatment, improved outcomes, and higher toxicity rates in PET-CT-staged patients emphasizes the need for a detailed risk-benefit assessment during planning and application of treatment modalities.

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Publication Details

Journal
Strahlentherapie und Onkologie
Published
2025-03-06
DOI
https://doi.org/10.1007/s00066-025-02377-0
Primary Topic
Lung Cancer Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Treatment of non-small cell lung cancer: advances following the introduction of PET-CT and IMRT/VMAT

Rami A. El Shafie, Mahalia Zoe Anczykowski, Manuel Guhlich, Tobias Raphael Overbeck et al.
Strahlentherapie und Onkologie
Lung Cancer Diagnosis and Treatment
article

Treatment of non-small cell lung cancer: advances following the introduction of PET-CT and IMRT/VMAT

Rami A. El Shafie, Mahalia Zoe Anczykowski, Manuel Guhlich, Tobias Raphael Overbeck, Markus Schirmer, Julian Muster, Niklas Josua Alt, Marcus Edelmann, Carla Marie Zwerenz, Martin Leu, Leif H. Dröge, Stefan Rieken, Friederike Braulke
article en

Abstract

In summary, refined RT/RCT strategies with PET-CT and IMRT/VMAT enable the intensification of multimodal treatment. Reduction of toxicities with IMRT/VMAT widens the therapeutic window. The coincidence of intensified treatment, improved outcomes, and higher toxicity rates in PET-CT-staged patients emphasizes the need for a detailed risk-benefit assessment during planning and application of treatment modalities.

Strahlentherapie und OnkologieVol. 201(11)
Universitätsmedizin Göttingen (DE), University of Göttingen (DE)
Openalex Percentile: Top 94%
Lung Cancer Diagnosis and Treatment
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Treatment of non-small cell lung cancer: advances following the introduction of PET-CT and IMRT/VMAT — Rami A. El Shafie, Mahalia Zoe Anczykowski, et al. · Strahlentherapie und Onkologie (2025) | TGRS Research Map | TGRS