Harnessing miR-16-5p-Loaded Exosomes from Adipose-Derived Stem Cells to Restore Immune Homeostasis in SLE Patients
ADSC-derived exosomes, through the miR-16-5p/LATS1 axis, offer a promising therapeutic approach for SLE by restoring immune equilibrium. This study highlights the potential of exosome-based therapies in modulating immune responses, providing a foundation for developing innovative treatments for autoimmune diseases.
Authors
- Sheng-Hao Li (ORCID: https://orcid.org/0000-0003-1207-3226)
- Ruixian Zhang (ORCID: https://orcid.org/0000-0001-7329-6218)
- Liming Yan (ORCID: https://orcid.org/0000-0003-0648-9604)
- Yinhong Zhang (ORCID: https://orcid.org/0000-0002-0893-2449)
- Fei Long (ORCID: https://orcid.org/0000-0002-6877-4403)
- Juan Chen
- W. Mao (ORCID: https://orcid.org/0009-0002-6465-0398)
Institutions
- Kunming Medical University (CN)
- First People's Hospital of Yunnan Province (CN)
- Kunming Third People's Hospital (CN)
- Yunnan Center for Disease Control And Prevention (CN)
- Third People's Hospital of Yunnan Province (CN)
Publication Details
- Journal
- Immunobiology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1016/j.imbio.2025.152885
- Citations
- 3
- Primary Topic
- Extracellular vesicles in disease
- Type
- article
- Field-Weighted Citation Impact
- 2.42