Real-world use and treatment outcomes of ceftazidime-avibactam in gram-negative bacterial infection in Taiwan: A multicenter retrospective study
Most patients receiving CAZ-AVI as targeted therapy in Taiwan with characteristics of older age, high SOFA scores, and high CCI scores. Receiving immunomodulators, higher SOFA score, and Enterobacter spp. infections were the significant factors associated with in-hospital mortality, whereas early initiating CAZ-AVI treatment and CAZ-AVI monotherapy are associated with better outcome.
Authors
- Tsung-Ying Yang (ORCID: https://orcid.org/0000-0001-5875-3011)
- Ya‐Ting Chang (ORCID: https://orcid.org/0000-0002-7560-7224)
- Yu‐Shan Huang
- Ching‐Tai Huang (ORCID: https://orcid.org/0000-0001-8624-4513)
- Yee‐Chun Chen (ORCID: https://orcid.org/0000-0002-1816-9010)
- Po‐Yu Liu (ORCID: https://orcid.org/0000-0001-8006-4917)
- Chien-Hao Tseng (ORCID: https://orcid.org/0000-0003-2098-8872)
- Peng-Hao Chang
- Po‐Liang Lu (ORCID: https://orcid.org/0000-0002-7423-6783)
- Yi‐Tsung Lin (ORCID: https://orcid.org/0000-0001-9940-7529)
Institutions
- Johns Hopkins University (US)
- Kaohsiung Medical University (TW)
- National Chung Hsing University (TW)
- National Health Research Institutes (TW)
- Kaohsiung Medical University Chung-Ho Memorial Hospital (TW)
- Taipei Veterans General Hospital (TW)
- Chang Gung Memorial Hospital (TW)
- Mackay Medical University (TW)
- Taichung Veterans General Hospital (TW)
- National Taiwan University Hospital (TW)
- Sidney Kimmel Comprehensive Cancer Center (US)
- Taipei Medical University (TW)
Publication Details
- Journal
- Journal of Infection and Public Health
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1016/j.jiph.2025.102735
- Citations
- 2
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.18
Funders
- Pfizer