Unraveling the genetic basis of subclinical atherosclerosis: Early genetic detection can improve cardiovascular prevention
This study showed that three genetic variants previously linked with CAD are associated with CAC in asymptomatic populations. Understanding these genetic factors, combined with conventional risk factors, could guide lifestyle changes or pharmacologic interventions to mitigate CAD risk before the disease becomes clinical.
Authors
- Francisco Alves de Sousa (ORCID: https://orcid.org/0000-0003-4113-3259)
- M I Mendonça (ORCID: https://orcid.org/0000-0001-5450-5213)
- G Guerra (ORCID: https://orcid.org/0000-0002-4673-1218)
- M Serrão (ORCID: https://orcid.org/0000-0002-7893-0043)
- E Henriques
- M Rodrigues (ORCID: https://orcid.org/0000-0002-9930-5028)
- Sónia Freitas
- Roberto Palma dos Reis (ORCID: https://orcid.org/0009-0002-5163-9763)
- Sofia Borges
- G.R. Abreu (ORCID: https://orcid.org/0009-0008-8772-8470)
- Débora Sá (ORCID: https://orcid.org/0009-0003-2722-3327)
- Ilídio Ornelas
- António Drumond
- Ana Célia Sousa
Institutions
- Universidade Nova de Lisboa (PT)
Publication Details
- Journal
- Revista Portuguesa de Cardiologia
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1016/j.repc.2025.01.003
- Citations
- 2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 3.63