Direction of TIS envelope electric field: Perpendicular to the longitudinal axis of the hippocampus
Our analysis revealed that the orientations of maximal modulation depth in the left hippocampus were perpendicular to its longitudinal axis under the current electrode configuration, but they shifted to parallel alignment when the electrode pairs were swapped. This directional specificity offers insights for optimizing TIS by aligning with structural features, presenting a potential strategy to enhance stimulation precision and broaden its clinical and research applications.
Authors
- Xiaolin Huo (ORCID: https://orcid.org/0000-0001-7416-3601)
- Cheng Zhang (ORCID: https://orcid.org/0000-0003-1512-2820)
- Weiyu Meng
- Guanghao Zhang (ORCID: https://orcid.org/0000-0002-6445-2271)
- Changzhe Wu
Institutions
- University of Chinese Academy of Sciences (CN)
Publication Details
- Journal
- Journal of Neuroscience Methods
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1016/j.jneumeth.2025.110416
- Citations
- 5
- Primary Topic
- Neural dynamics and brain function
- Type
- article
- Field-Weighted Citation Impact
- 7.16
Funders
- National Natural Science Foundation of China
- Key Technologies Research and Development Program
- National Key Research and Development Program of China
- Beijing Science and Technology Planning Project