Comparison of measurements obtained by an optical low coherence interferometry biometer and a swept source optical coherence tomography biometer in two datasets

Objectives The objective of this study was to compare the similarity of biometry measurements between the Lenstar ® (Haag-Streit AG, Switzerland), which uses optical low coherence reflectometry, and Anterion ® (Heidelberg Engineering, Heidelberg, Germany), which uses swept-source optical coherence tomography technology, in two datasets. Materials and Methods This retrospective study was conducted at a single tertiary referral centre. Biometry measurements from Lenstar and Anterion were collected in two datasets. Dataset 1 was collected between November 2021 and June 2022, with scans taken on the same eye on different days by different technicians. Dataset 2 was collected between September 2022 and November 2022, with scans taken on the same day by the same operator. Results A total of 196 eyes from 130 patients across two datasets were included in the study. Axial length (AL), flat keratometry (K1), steep keratometry (K2) and anterior chamber depth (ACD) showed excellent similarity, but white-to-white (WTW) reproducibility was poor to moderate in both samples. There was no statistical difference in AL and K1 between the biometers in both datasets. Statistical differences between the biometers were found for lens thickness (LT) and WTW in both datasets and ACD in one dataset. Conclusion The devices showed similar measurements and consistency for AL. Scanning patients on different days with different technicians yielded similar results to scanning patients on the same day by a single technician. These findings have implications for short eyes and fourth-generation formulae, where the inclusion of ACD, LT and WTW in the lens calculation formula can result in differences in calculated intraocular lens power.