Circadian rhythmicity of symptomatic phenotypes in multiple sclerosis: the CircaMS study protocol and feasibility of biomarker collection

The CircaMS project and its associated procedures have been reviewed and approved by the Queen's University Health Sciences and Affiliated Teaching Hospitals research ethics board (File number: 6039383). Participants provide informed consent to participate, and their data will not be identifiable in any publication or report. All documents are stored securely and only accessible by study staff and authorised personnel. The results will be presented to academic and lay audiences via national/international conferences, publications in peer-reviewed journals, social media and through an official website created to engage pwMS, caregivers, clinicians and researchers.