Combination of hemochromatosis and primary biliary cholangitis

A clinical case of an extremely rare morphologically verified combination of primary biliary cholangitis and hemochromatosis in a patient is presented. A brief description and literature reference on these diseases are given from the standpoint of a modern approach to diagnostics, classification, clinical manifestations and treatment. The presented observation considers the course of the disease in a patient from the onset to the present time, including the stage of self-induced cessation of taking the necessary medications and seeking medical help, which led to rapid progression of the disease with pronounced clinical manifestations with the appearance of a typical color of the skin, the appearance of xanthelasma, hepatosplenomegaly and hepatocellular insufficiency. The data of laboratory and instrumental examination conducted in various clinics are analyzed. It is important to note that liver cirrhosis as a result of primary biliary cholangitis and hemochromatosis has a very unfavorable prognosis, and the treatment is comprehensive.