USING PULSED LASER ABLATION IN LIQUID TECHNIQUE TO SYNTHESIS AND CHARACTERIZATION OF FEO AT AU NPs CORE-SHELL: EVALUATION OF ANTIMICROBIAL ACTIVITY

Medical nanotechnology has become a cutting-edge and effective method for curing some of the most difficult medical problems. Gold, silver, and other inorganic nanomaterials have demonstrated potential antibacterial efficacies. Interestingly, because of their ability to interact well with biological systems, the ease of surface manipulation and the excellent optical properties characteristic of gold (FeO at Au NPs) core shell has drawn particular attention. Coating one nanomaterial with another results in a composite of two nanoparticles (NPs), enhancing both the physical and chemical properties. This enhancement increases its effectiveness, particularly in medical applications. Escherichia coli, Staphylococcus aureus, Bacillus subtitles, and Klebsiella pneumonia are the most common enteric bacterial human pathogens that cause diarrhea in both children and adults. Their shape negatively impacts the human immune system. Then, the X-ray diffraction technique was used to analyze the core-shell structure of these particles. We have looked into the crucial impact that average particle size has on the suppression of the abovementioned bacterial species. The size of the gold NPs generated in liquid by pulsed laser ablation in liquid approach was shown by ultraviolet-visible spectroscopy to be in the 290-1,100 nm range. The results show that the surface plasmon resonance peak of gold occurs at ~ 545 nm and is within the range of 290-1,100 nm. On the other hand, iron shows its maximum absorption peak at ~ 0.45 within the range of 200-350 nm. Additionally, the search illustrates an additional absorption peak attributed to FeO at Au core-shell structure at 555 nm within the range of 290-1,100 nm. Transmission electron microscope analysis revealed that particle sizes were < 50 nm during the preparation of the core-shell structure.