Phase II Trial of Pembrolizumab in Combination With Bevacizumab for Untreated Melanoma Brain Metastases

Pembrolizumab with bevacizumab was well tolerated and demonstrated substantial activity in patients with untreated MBM with promising OS, justifying further evaluation of this regimen.

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Publication Details

Journal
Journal of Clinical Oncology
Published
2025-03-06
DOI
https://doi.org/10.1200/jco-24-02219
Citations
8
Primary Topic
Cancer Immunotherapy and Biomarkers
Type
article
Field-Weighted Citation Impact
8.36
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article

Phase II Trial of Pembrolizumab in Combination With Bevacizumab for Untreated Melanoma Brain Metastases

Harriet M. Kluger, Adebowale Adeniran, Thuy Tran, Upendra P. Hegde et al.
8 citations
Journal of Clinical Oncology
Cancer Immunotherapy and Biomarkers
8.36
article

Phase II Trial of Pembrolizumab in Combination With Bevacizumab for Untreated Melanoma Brain Metastases

Harriet M. Kluger, Adebowale Adeniran, Thuy Tran, Upendra P. Hegde, Zeynep Eroglu, Gail D. Anderson, Sarah B. Goldberg, Amit Mahajan, Peter Forsyth, Joseph Markowitz, Justine V. Cohen, Veronica Chiang, Nikhil I. Khushalani, Barbara Johnson, Sarah A. Weiss, Lucia B. Jilaveanu, Wei Wei, Matthew R Austin, Dijana Djureinovic, Cecily Piteo, Mario Sznol
article en
8 citations

Abstract

Pembrolizumab with bevacizumab was well tolerated and demonstrated substantial activity in patients with untreated MBM with promising OS, justifying further evaluation of this regimen.

Journal of Clinical OncologyVol. 43(14)
Rutgers, The State University of New Jersey (US), University of Connecticut (US), Moffitt Cancer Center (US), Yale University (US), Dana-Farber Cancer Institute (US)
Openalex Percentile: Top 2%
Cancer Immunotherapy and Biomarkers
8.36
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