The Potential Link between Removable Dentures and Alzheimer's Disease

Alzheimer's disease (AD) is a common neurocognitive disorder that impacts millions of people globally. The last few decades have seen considerable progress in AD research, while much of the pathophysiology and associated risk factors are still up for debate. Recent studies suggested the association between oral health and the development of AD, especially periodontal pathogens. Edentulism and partial edentulism are common in older people and are frequently addressed with the use of removable dentures. However, RDs can disturb the homeostasis of oral microflora over time. This study aims to explore the possible connections between the use of removable dentures and AD by reviewing existing literature. The findings indicate that the use of removable dentures in individuals with edentulism and partial edentulism is associated with an increased prevalence of periodontal pathogens. Considering that AD primarily affects older individuals, who frequently require rehabilitation with removable dentures, these findings highlight the potential relationship between these factors. However, further detailed research is necessary to clarify this association.