The cell-fate decision of dental follicle stem cells (DFSCs) with porcine corneal extracellular matrix (ECM)
The present study demonstrated that DFSCs cultured on the porcine corneal ECM can differentiate mainly into keratocytes-like and partially into corneal endothelial-like cells, exhibiting strong cell-ECM adhesion and regulation of growth factors. Provide insights into the therapeutic application potential of dental-derived stem cells and SC-CO<sub>2</sub> decellularized tissue for corneal diseases.
Authors
- Ming‐Hua Ho (ORCID: https://orcid.org/0000-0001-6620-4207)
- Chung-Hsing Li (ORCID: https://orcid.org/0000-0002-6718-5500)
- Yong-Ren Chen
- Kuan-Ming Lin
Institutions
- Tri-Service General Hospital (TW)
- National Taiwan University of Science and Technology (TW)
- National Taiwan University Hospital (TW)
- National Defense Medical Center (TW)
Publication Details
- Journal
- Journal of Dental Sciences
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1016/j.jds.2025.02.019
- Primary Topic
- Corneal Surgery and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Taiwan University of Science and Technology
- Tri-Service General Hospital