Anti-arthritic effects of polyunsaturated fatty acid–rich supplementation combined with selective soluble epoxide hydrolase inhibitors in a collagen-induced arthritis mouse model
This study highlights the potential of ω-3 PUFAs combined with sEHi as the novel protective effect for RA.
Authors
- Rintaro Saito (ORCID: https://orcid.org/0000-0001-9084-8045)
- Tsuneyo Mimori (ORCID: https://orcid.org/0000-0003-0016-2053)
- Hideaki Tsuji (ORCID: https://orcid.org/0000-0002-2521-246X)
- Yoichi Nakayama (ORCID: https://orcid.org/0000-0002-8130-4350)
- Kosaku Murakami (ORCID: https://orcid.org/0000-0001-5981-4648)
- Hirotake Tsukamoto (ORCID: https://orcid.org/0000-0003-3214-1652)
- Hajime Yoshifuji (ORCID: https://orcid.org/0000-0001-7082-4900)
- Ryosuke Hiwa (ORCID: https://orcid.org/0000-0001-6968-5712)
- Ran Nakashima (ORCID: https://orcid.org/0000-0001-6247-0647)
- Akio Morinobu (ORCID: https://orcid.org/0000-0002-4672-638X)
- Akira Ōnishi (ORCID: https://orcid.org/0000-0002-3120-1273)
- Masao Tanaka (ORCID: https://orcid.org/0000-0002-8942-2933)
- Shuji Akizuki (ORCID: https://orcid.org/0000-0001-9670-9206)
- Mirei Shirakashi (ORCID: https://orcid.org/0000-0003-1135-0463)
- Akiko Yoshida
- Yunhong Hotta
Institutions
- Kyoto University (JP)
- Institute for Rheumatic Diseases (Japan) (JP)
- Takeda (France) (FR)
- Takeda (Japan) (JP)
Publication Details
- Journal
- Modern Rheumatology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1093/mr/roaf019
- Citations
- 1
- Primary Topic
- Eicosanoids and Hypertension Pharmacology
- Type
- article
- Field-Weighted Citation Impact
- 1.11
Funders
- Japan Society for the Promotion of Science