Ten-year follow-up of degenerative spinal lesions on radiographs and MRI in axial spondyloarthritis: results of the DESIR (DEvenir des spondylarthropathies indifférenciées récentes) cohort
Question The long-term evolution of spinal DLs in axSpA on radiographs and MRI, and the associated factors, is currently poorly understood. Findings Spinal DLs, although common, progress slowly over 10Y, but in patients with a higher BMI or exposed to bDMARDs, the progression is faster. Clinical relevance Understanding the progression of spinal DLs in axSpA helps to refine the interpretation of long-term imaging, limit diagnostic errors and optimise management strategies, particularly in patients with the highest risk of progression of these lesions.
Authors
- Laura Pina Vegas (ORCID: https://orcid.org/0000-0002-2735-1148)
- F. van Gaalen (ORCID: https://orcid.org/0000-0001-8448-7407)
- Alain Saraux (ORCID: https://orcid.org/0000-0002-8454-7067)
- M. van Lunteren (ORCID: https://orcid.org/0000-0002-0601-4863)
- Damien Lœuille (ORCID: https://orcid.org/0000-0001-8204-5701)
- Pascal Claudepierre
- C. Morizot (ORCID: https://orcid.org/0000-0002-3512-2409)
- Sofia Ramiro
- M. Reijnierse (ORCID: https://orcid.org/0000-0002-6906-1851)
- A. Feydy (ORCID: https://orcid.org/0000-0002-9772-3947)
- Désirée van der Heijde
- E.C. Newsum
Institutions
- Inserm (FR)
- Université de Bretagne Occidentale (FR)
- Université Paris-Est Créteil (FR)
- Leiden University Medical Center (NL)
- Centre Hospitalier Universitaire Henri-Mondor (FR)
- Hôpital Cochin (FR)
- Assistance Publique – Hôpitaux de Paris (FR)
- Centre Hospitalier Régional et Universitaire de Nancy (FR)
- Ziekenhuis Nij Smellinghe (NL)
- Zuyderland Medisch Centrum (NL)
Publication Details
- Journal
- European Radiology
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1007/s00330-025-11432-4
- Citations
- 4
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 6.67
Funders
- Pfizer
- Biogen
- Assistance publique-Hôpitaux de Paris