Isoflavone Constituents of the Underground Parts of <i>Iris florentina</i> and Their Inhibitory Activity on the Formation of Advanced Glycation End Products

Two new isoflavone glucosides, irisolone 4'-O-[O-β-d-glucopyranosyl-(1→6)-O-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside] (1) and iriskashmirianin 4'-O-[O-β-d-glucopyranosyl-(1→6)-O-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside] (2) were isolated from the underground parts of Iris florentina (Iridaceae). The structures of 1 and 2 were determined based on extensive spectroscopic data analyses and hydrolytic cleavage results. The isoflavone derivatives previously isolated from this plant were evaluated for their ability to inhibit the formation of advanced glycation end products.

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Publication Details

Journal
Chemical and Pharmaceutical Bulletin
Published
2025-03-06
DOI
https://doi.org/10.1248/cpb.c24-00776
Citations
2
Primary Topic
Phytoestrogen effects and research
Type
article
Field-Weighted Citation Impact
2.94
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article

Isoflavone Constituents of the Underground Parts of Iris florentina and Their Inhibitory Activity on the Formation of Advanced Glycation End Products

Nana Fujita, Yuka Yoshizawa, Akihito Yokosuka, Yoshihiro Mimaki
2 citations
Chemical and Pharmaceutical Bulletin
Phytoestrogen effects and research
2.94
article

Isoflavone Constituents of the Underground Parts of Iris florentina and Their Inhibitory Activity on the Formation of Advanced Glycation End Products

Nana Fujita, Yuka Yoshizawa, Akihito Yokosuka, Yoshihiro Mimaki
article en
2 citations

Abstract

Two new isoflavone glucosides, irisolone 4'-O-[O-β-d-glucopyranosyl-(1→6)-O-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside] (1) and iriskashmirianin 4'-O-[O-β-d-glucopyranosyl-(1→6)-O-β-d-glucopyranosyl-(1→6)-β-d-glucopyranoside] (2) were isolated from the underground parts of Iris florentina (Iridaceae). The structures of 1 and 2 were determined based on extensive spectroscopic data analyses and hydrolytic cleavage results. The isoflavone derivatives previously isolated from this plant were evaluated for their ability to inhibit the formation of advanced glycation end products.

Chemical and Pharmaceutical BulletinVol. 73(3)
Tokyo University of Pharmacy and Life Sciences (JP)
Openalex Percentile: Top 11%
Phytoestrogen effects and research
2.94
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