SIRT7 affects the proliferation and apoptosis of papillary thyroid cancer cells by desuccinylation of LATS1
Taken together, silencing of SIRT7 promotes the succinylation of LATS1 to enhance LATS1 stability, thus inhibiting the progression of PTC. Therefore, SIRT7 and LATS1 may become novel and potential therapeutic targets for PTC.
Authors
- 剛史 三浦
- Qing Li (ORCID: https://orcid.org/0000-0002-7930-2145)
Institutions
- Beihua University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1186/s12885-025-13779-9
- Citations
- 3
- Primary Topic
- Sirtuins and Resveratrol in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 3.67