Synthesis and Characterization of tert-butyl 3-(((2-hydroxynaphthalen1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1- carboxylate: A piperidine clubbed Boc protected versatile building block for multi functionalized chemical reactions

A novel fluorine containing Schiff base tert-butyl 3-(((2-hydroxynaphthalen-1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1-carboxylate (RSB1) a possible potent reactive building block was synthesized by condensing fluorine bearing piperidine containing boc protected amine derivative with the 2hydroxy napthaldehyde using simple condensation method in good yield and high purity. Structure characterization of the title compound was done by, 1H-NMR, 13C-NMR and HRMS spectral analysis

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Publication Details

Journal
Journal of Applied Research and Technology
Published
2025-02-28
DOI
https://doi.org/10.22201/icat.24486736e.2025.23.1.2611
Primary Topic
Chemical Synthesis and Analysis
Type
article
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article

Synthesis and Characterization of tert-butyl 3-(((2-hydroxynaphthalen1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1- carboxylate: A piperidine clubbed Boc protected versatile building block for multi functionalized chemical reactions

K. Sunil, K. Pruthviraj
Journal of Applied Research and Technology
Chemical Synthesis and Analysis
article

Synthesis and Characterization of tert-butyl 3-(((2-hydroxynaphthalen1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1- carboxylate: A piperidine clubbed Boc protected versatile building block for multi functionalized chemical reactions

K. Sunil, K. Pruthviraj
article en

Abstract

A novel fluorine containing Schiff base tert-butyl 3-(((2-hydroxynaphthalen-1-yl)methylene)amino)-4-(4-(trifluoromethyl)phenyl)piperidine-1-carboxylate (RSB1) a possible potent reactive building block was synthesized by condensing fluorine bearing piperidine containing boc protected amine derivative with the 2hydroxy napthaldehyde using simple condensation method in good yield and high purity. Structure characterization of the title compound was done by, 1H-NMR, 13C-NMR and HRMS spectral analysis

Journal of Applied Research and TechnologyVol. 23(1)
Sri Siddhartha Medical College (IN)
Openalex Percentile: Top 96%
Chemical Synthesis and Analysis
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