Enhanced systemic oxidative stress response in patients with idiopathic inflammatory myopathies
IIM are characterized by a global pro-oxidant imbalance reflected by enhanced HP generation in serum. Furthermore, muscle weakening without active signs of muscle damage may be related to the increased local and systemic oxidative stress response, suggesting non-inflammatory pathomechanism of the disease that our technically undemanding assay may evaluate.
Authors
- Krzysztof Wójcik (ORCID: https://orcid.org/0000-0001-9786-2499)
- Stanisława Bazan‐Socha (ORCID: https://orcid.org/0000-0001-9634-0963)
- Jan G. Bazan (ORCID: https://orcid.org/0000-0002-9738-7007)
- Magdalena Olchawa (ORCID: https://orcid.org/0000-0003-3276-7671)
- Lech Zaręba (ORCID: https://orcid.org/0000-0002-2221-614X)
- Anna Mikołajczyk-Korona (ORCID: https://orcid.org/0000-0001-7590-7318)
- Bogdan Jakieła (ORCID: https://orcid.org/0000-0003-0444-981X)
- Piotr Kuszmiersz (ORCID: https://orcid.org/0000-0002-2031-6657)
- Tadeusz Sarna (ORCID: https://orcid.org/0000-0002-7693-5756)
- Mateusz Socha (ORCID: https://orcid.org/0000-0003-3639-0867)
- Jakub Pięta (ORCID: https://orcid.org/0000-0003-3527-4768)
- Agnieszka Padjas (ORCID: https://orcid.org/0000-0001-6492-6521)
- Daniel P. Potaczek (ORCID: https://orcid.org/0000-0003-0324-8506)
- Joanna Kosałka-Węgiel (ORCID: https://orcid.org/0000-0003-1013-2253)
- Radosław Dziedzic (ORCID: https://orcid.org/0000-0003-0321-3557)
Institutions
- Jagiellonian University (PL)
- Philipps University of Marburg (DE)
- Lodz University of Technology (PL)
- Institute of Computer Science (PL)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1186/s13075-025-03511-0
- Citations
- 3
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 4.06
Funders
- Uniwersytet Jagielloński Collegium Medicum