SDF-1 alleviates osteoarthritis by resolving mitochondrial dysfunction through the activation of the Sirt3/PGC-1α signalling pathway
SDF-1 can alleviate OA by resolving mitochondrial dysfunction through the activation of the Sirt3/PGC-1α signalling pathway, and therefore, SDF-1 may be a good candidate as a new treatment for OA.
Authors
- Xiaoying Zhu (ORCID: https://orcid.org/0000-0001-6988-8026)
- Tianqi Dai
- Jingyao Yan (ORCID: https://orcid.org/0000-0002-3603-0514)
- Yanli Wang (ORCID: https://orcid.org/0000-0002-2119-8971)
- Shuya Wang (ORCID: https://orcid.org/0000-0002-1031-8907)
- Yanping Zhao (ORCID: https://orcid.org/0000-0002-0224-0417)
- Yan Liang (ORCID: https://orcid.org/0000-0002-8835-0480)
- Dan Lin (ORCID: https://orcid.org/0009-0006-3235-6572)
- Zhiyi Zhang (ORCID: https://orcid.org/0000-0001-8345-6588)
Institutions
- Harbin Medical University (CN)
Publication Details
- Journal
- Arthritis Research & Therapy
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1186/s13075-025-03509-8
- Citations
- 4
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 6.67
Funders
- National Natural Science Foundation of China