Elastase reduces background autofluorescence in ALK fluorescence in situ hybridization assays for lung cancers
This novel elastase pretreatment protocol addresses autofluorescence interference in lung tissues and can significantly improve the reliability of FISH assays for targeted therapy decisions.
Authors
- Tse‐Ching Chen (ORCID: https://orcid.org/0000-0003-2532-7328)
- Hsiao-Chun Wu
- Sheng‐Chi Hsu
- Tsai‐Hsien Hung (ORCID: https://orcid.org/0000-0002-6173-0862)
- Kwai‐Fong Ng
Institutions
- Chang Gung University (TW)
- Chang Gung Memorial Hospital (TW)
Publication Details
- Journal
- Biomedical Journal
- Published
- 2025-03-06
- DOI
- https://doi.org/10.1016/j.bj.2025.100840
- Citations
- 3
- Primary Topic
- Lung Cancer Treatments and Mutations
- Type
- article
- Field-Weighted Citation Impact
- 4.56
Funders
- Chang Gung Memorial Hospital
- Ministry of Health and Welfare
- National Science and Technology Council