Meglitinide Drugs Member as a Compendium

Background Meglitinides (glinides(are a class of antidiabetic drugs used for diminishing the postprandial glucose level by enhancing insulin release from beta-cells of the pancreas. Objectives This review is done to insight into the pharmacokinetic and pharmacological aspects of Meglitinides drugs. Material and Methods The details of information that present in this review were picked up from numerous scientific sites in online net such as Scopus, PubMed, and others. As well articles with just abstract was omitted. Results Glinides involved three types of drugs named Repaglinide (Prandin), Nateglinide (Starlix), and Mitiglinide (Glufast). Glinides can be used alone or co administered with other antidiabetic drug such as metformin, whereas sulphonylurea drug has exception from co administration with glinides members due to the same site of action of both class that lead to excessive side effect. Conclusion Glinides are another class of antidiabetic drugs, that act by reducing post-prandial glucose and hemoglobin A1C levels. Weight gain and hypoglycemia are the most common unwanted effects of the use of these drugs.