Hemotropic mycoplasmas (hemoplasmas) in indigenous populations and their dogs living in reservation areas, Brazil
Although hemoplasma infection has been widely described in animals, a few studies have been conducted involving human populations, mostly as case reports. This was a cross-sectional epidemiological study that accessed hemoplasma infection in individuals and dogs from ten Indigenous communities of southern and southeastern Brazil. A total of 23/644 (3.6%) individuals of ten Indigenous communities tested positive to hemoplasmas by quantitative polymerase chain reaction (qPCR) (cycle threshold; Ct ≤ 34.4), with 3/644 (0.5%) Mycoplasma haemocanis detection. In addition, 91/416 (21.9%) dogs were positive to hemoplasmas by qPCR, with 54/91 (59.3%) for M. haemocanis, 27/91 (29.7%) for Candidatus Mycoplasma haematoparvum, and 10/91 (11.0%) for both. Molecular diagnosis of M. haemocanis in Indigenous people herein may be consequence of daily close contact with dogs and different potential vectors. Although apparently healthy individuals, hemoplasma infection should be considered as differential diagnosis in likely overexposed populations, such as Indigenous individuals.
Authors
- Andrea Pires dos Santos (ORCID: https://orcid.org/0000-0002-1037-970X)
- Alexander Welker Biondo (ORCID: https://orcid.org/0000-0002-4182-5821)
- Rogério Giuffrida (ORCID: https://orcid.org/0000-0002-2380-4349)
- Paul D. Shaw (ORCID: https://orcid.org/0000-0002-0202-1150)
- M. Johnson (ORCID: https://orcid.org/0000-0001-7757-8458)
- Rebecca P. Wilkes (ORCID: https://orcid.org/0000-0003-4846-0439)
- Leandro Meneguelli Biondo (ORCID: https://orcid.org/0000-0001-7554-1520)
- Jobin Jose Kattoor (ORCID: https://orcid.org/0000-0002-0391-0064)
- Vamilton Álvares Santarém (ORCID: https://orcid.org/0000-0002-7065-1138)
- Louise Bach Kmetiuk (ORCID: https://orcid.org/0000-0001-6579-1278)
- Joanne B. Messick
- Fabiano Borges Figueiredo (ORCID: https://orcid.org/0000-0001-6861-0997)
- Ashley Wallington
Institutions
- University of British Columbia (CA)
- Purdue University West Lafayette (US)
- Universidade do Oeste Paulista (BR)
- Ministério da Saúde (BR)
- IDEXX Laboratories (United States) (US)
- Fundação Carlos Chagas (BR)
- Fundação Oswaldo Cruz (BR)
- Universidade Federal do Paraná (BR)
Publication Details
- Journal
- Scientific Reports
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1038/s41598-025-87938-0
- Citations
- 7
- Primary Topic
- Vector-borne infectious diseases
- Type
- article
- Field-Weighted Citation Impact
- 14.33
Funders
- Conselho Nacional de Desenvolvimento Científico e Tecnológico