Clinical Significance of RBM15 in Gastric Cancer: A Multi-Database Validation

RBM15 mRNA is upregulated in GC and significantly associated with a favorable prognosis. It correlates with clinicopathological features, is enriched in DNA replication processes, and is commonly mutated. Its expression also impacts immune cell infiltration and drug sensitivity, indicating its potential as a prognostic marker and therapeutic target in GC.

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Publication Details

Journal
Current Medicinal Chemistry
Published
2025-03-07
DOI
https://doi.org/10.2174/0109298673356198250217100226
Primary Topic
RNA modifications and cancer
Type
article
Field-Weighted Citation Impact
0.00
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article

Clinical Significance of RBM15 in Gastric Cancer: A Multi-Database Validation

Mingxu Da, Tong Liang, Zhong Yang, Chongyang Ding
Current Medicinal Chemistry
RNA modifications and cancer
article

Clinical Significance of RBM15 in Gastric Cancer: A Multi-Database Validation

Mingxu Da, Tong Liang, Zhong Yang, Chongyang Ding
article en

Abstract

RBM15 mRNA is upregulated in GC and significantly associated with a favorable prognosis. It correlates with clinicopathological features, is enriched in DNA replication processes, and is commonly mutated. Its expression also impacts immune cell infiltration and drug sensitivity, indicating its potential as a prognostic marker and therapeutic target in GC.

Current Medicinal ChemistryVol. 33(6)
JiangSu Armed Police General Hospital (CN), Gansu Provincial Hospital (CN), Lanzhou University (CN)
Openalex Percentile: Top 96%
RNA modifications and cancer
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