Cancer Immunotherapies: Navigating the Immune Landscape
Biotechnology has paved the way for the development of cancer therapeutics that harness biological systems. Cancer immunotherapy (CI) is a pivotal and swiftly progressing therapeutic modality, alongside surgical intervention, cytotoxic chemo-therapy, radiation therapy, and targeted therapy. Therefore, this is the fifth cornerstone of cancer management. Biotechnological pharmaceuticals are superior modalities for combat-ing neoplastic conditions when juxtaposed with conventional chemical therapeutics. Consid-ering empirical evidence, it can be posited that biotechnology exhibits a heightened level of precision in targeting malignant cells associated with cancer, thereby minimizing collateral damage compared to conventional chemotherapeutic approaches. Furthermore, this ap-proach harnesses the inherent capabilities of the immune system to impede cancer recur-rence, thereby facilitating a more proactive therapeutic intervention, as opposed to a mere deleterious remedy. Novel cancer immunotherapeutic medications, along with uncomplicat-ed methodologies that enable the quantitative evaluation of the effectiveness of compounds capable of modifying T cell-mediated, tumor antigen-specific immune responses, play a pivotal role in the assessment process. This highlights the considerable promise of immuno-therapies, monoclonal antibodies, and an array of biotechnological products in a relentless battle against cancer.
Authors
- Darshan R. Telange (ORCID: https://orcid.org/0000-0003-3016-8237)
- V. Mishra (ORCID: https://orcid.org/0000-0002-0193-9736)
- Alaa A. A. Aljabali (ORCID: https://orcid.org/0000-0002-9519-6338)
- Kalvatala Sudhakar
- Yachana Mishra (ORCID: https://orcid.org/0000-0002-3467-0518)
- Pramoda Kumar Sahoo (ORCID: https://orcid.org/0000-0002-3042-3659)
- Rakesh Kumar (ORCID: https://orcid.org/0009-0005-8723-441X)
- Shubham Kumar (ORCID: https://orcid.org/0000-0001-7188-0285)
- Joseph Finian Maleme
- Oshin Maiti
Institutions
- Lovely Professional University (IN)
- Datta Meghe Institute of Higher Education and Research (IN)
- Yarmouk University (JO)
Publication Details
- Journal
- Current Cancer Drug Targets
- Published
- 2025-03-06
- DOI
- https://doi.org/10.2174/0115680096346735250218110708
- Primary Topic
- CAR-T cell therapy research
- Type
- article
- Field-Weighted Citation Impact
- 0.00