Knockdown of FKBP12.6 may Cause Bladder Dysfunction in Mice by Affecting IP3R/TRPM4 Function

The expression of FKBP12.6 was decreased in the bladder of PBOO mice, and the deletion of FKBP12.6 may lead to bladder dysfunction in mice by affecting the functional activity of IP3R/TRPM4.

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Publication Details

Journal
Current Medicinal Chemistry
Published
2025-03-07
DOI
https://doi.org/10.2174/0109298673321084241205121141
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
0.00
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article

Knockdown of FKBP12.6 may Cause Bladder Dysfunction in Mice by Affecting IP3R/TRPM4 Function

Hao Zhou, Kui Zhai, Eric Nyirimigabo, Yangcai Wang et al.
Current Medicinal Chemistry
Hormonal Regulation and Hypertension
article

Knockdown of FKBP12.6 may Cause Bladder Dysfunction in Mice by Affecting IP3R/TRPM4 Function

Hao Zhou, Kui Zhai, Eric Nyirimigabo, Yangcai Wang, Ronghua Wu, Yu Liu, Jun Wang, Zheng Ji, Jiang Zhao
article en

Abstract

The expression of FKBP12.6 was decreased in the bladder of PBOO mice, and the deletion of FKBP12.6 may lead to bladder dysfunction in mice by affecting the functional activity of IP3R/TRPM4.

Current Medicinal ChemistryVol. 33(10)
Army Medical University (CN), Dalian Medical University (CN), Chinese Academy of Sciences (CN), Second Affiliated Hospital of Chongqing Medical University (CN), Institute of Biophysics (CN), Southwest Hospital (CN), Chinese People's Liberation Army (CN), Chongqing Medical University (CN)
Openalex Percentile: Top 94%
Hormonal Regulation and Hypertension
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