Artemisinin regulates cell proliferation, apoptosis, and the inflammatory response of human dental pulp stem cells through the p53 signaling pathway under LPS-induced inflammation
This study demonstrates that ART facilitates the alleviation of inflammation and preserves the viability of HDPSCs. Therefore, ART may serve as a promising therapeutic drug for the repair and regeneration of dental pulp in the treatment of deep caries and reversible pulpitis.
Authors
- Enkang Tong
- Cuicui Zhao (ORCID: https://orcid.org/0009-0000-7747-2039)
- Rongrong Nie
- Xiangfeng Meng (ORCID: https://orcid.org/0000-0001-6080-4682)
- Yuan Sui
- Xiaofei Dong (ORCID: https://orcid.org/0000-0002-5582-1629)
Institutions
- Stomatology Hospital (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- International Immunopharmacology
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1016/j.intimp.2025.114396
- Citations
- 3
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 4.88