The effects of urine alkalinization on kidney function in critically ill patients with COVID-19: a proof-of-concept randomized clinical trial
While urine alkalinization is feasible and can increase urine pH, we could not demonstrate differences in AKI rates or changes in urine [TIMP-2]x[IGFBP7] concentrations in critically ill COVID-19 patients.
Authors
- John A. Kellum (ORCID: https://orcid.org/0000-0003-1995-2653)
- Nuttha Lumlertgul (ORCID: https://orcid.org/0000-0003-1506-4253)
- J. Powell-Tuck
- Marlies Ostermann (ORCID: https://orcid.org/0000-0001-9500-9080)
- Sunita Sardiwal
- Moncy Mathew
Institutions
- St Thomas' Hospital (GB)
- Chulalongkorn University (TH)
- University of Pittsburgh (US)
- Guy's and St Thomas' NHS Foundation Trust (GB)
- King Chulalongkorn Memorial Hospital (TH)
Publication Details
- Journal
- Intensive Care Medicine Experimental
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1186/s40635-025-00739-7
- Primary Topic
- Thermal Regulation in Medicine
- Type
- article
- Field-Weighted Citation Impact
- 0.00