Arrival time mapping with 15O-gas PET for cerebrovascular steno-occlusive diseases: a comparative study with CT perfusion
The present method generates arrival-time maps with <sup>15</sup>O-gas PET by applying optimized kinetic analysis to dynamic [<sup>15</sup>O]-CO<sub>2</sub> images acquired using a state-of-the-art, high-sensitivity clinical PET scanner. Additional arrival time information for conventional PET parameters of CBF and oxygen metabolism may facilitate a more comprehensive understanding of the hemodynamic status in cerebrovascular steno-occlusive diseases.
Authors
- Tomomi Ohmura
- Aya Watanabe (ORCID: https://orcid.org/0000-0003-3123-489X)
- Hiroyuki Yamamoto (ORCID: https://orcid.org/0000-0002-1344-6525)
- Kaoru Sato (ORCID: https://orcid.org/0000-0002-6552-3684)
- Masanobu Ibaraki (ORCID: https://orcid.org/0000-0002-4280-6470)
- Yuki Shinohara (ORCID: https://orcid.org/0000-0001-6586-4086)
- Toshibumi Kinoshita
Institutions
- Kubota (Japan) (JP)
- Research Institute for Brain and Blood Vessels Akita (JP)
- Institute of Brain and Blood Vessels (JP)
Publication Details
- Journal
- EJNMMI Research
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1186/s13550-025-01209-7
- Citations
- 5
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 6.80
Funders
- Akita Prefectural University
- Siemens Healthineers
- Japan Society for the Promotion of Science