Mitochondrial DNA variation and intervertebral disc degeneration: a genotypic analysis in a South African cohort
This study was able to generate genotypic information for a South African cohort for both reported and understudied mutations. Furthermore, the identification of higher mutant allele frequencies for C16223T, A10398G and A8536G highlights the importance of considering these mutations in future studies using a larger cohort.
Authors
- Brendon Pearce (ORCID: https://orcid.org/0000-0002-7501-5771)
- Megan Collins (ORCID: https://orcid.org/0009-0002-4126-4777)
Institutions
- Stellenbosch University (ZA)
Publication Details
- Journal
- Molecular Biology Reports
- Published
- 2025-03-07
- DOI
- https://doi.org/10.1007/s11033-025-10394-6
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universiteit Stellenbosch